- It is The first Institute of Child health in the Country.
- It is The only Institute of Child health in the state of Andhra Pradesh.
- It is The only speciality hospital for Women and Children in the State of Andhra Pradesh.
- The first Neonatal unit with post of First Professor of Neonatology in the country was established in Niloufer Hospital.
- One of the First Social Paediatrics unit was started in Niloufer Hospital.
- It is the First Paediatrics Surgery Super Speciality unit recognized by M.C.I for Paediatrics surgery M.C.H course in the country.
- It is the First in the Country to have a Neonatal surgical unit.
- The First unit for emergency Paediatrics services in the Country was established in Niloufer hospital.
- One of the First School health Department was created in Niloufer hospital.
- It also has the School for mentally retarded established.
- The nutrition ward started in collaboration with N.I.N from the inception of the National Institute of Nutrition.
- Paediatrics cardiology, Paediatrics Neurology and Paediatrics Psychiatry units established four decades back.
- Round the clock Lab facilities available.
- It is the only peripheral teaching hospital with CT-Scan facility.
- Niloufer hospital has been identified for Centre of excellence on Paediatric H.I.V / AIDS and Paediatric regional centre for A.R.T.
- A councelling centre for infant and young child feeding, Adolescents (Youth friendly teen clinic), Women and child abuse, awareness of rights is being established in collaboration with Women development and child welfare department, Government of Andhra Pradesh.
- Niloufer hospital has a unique Architecture with a large courtyard and well lighted units with perfect engineering.
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